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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SRF
All Species:
23.94
Human Site:
S224
Identified Species:
37.62
UniProt:
P11831
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11831
NP_003122.1
508
51593
S224
T
C
L
N
S
P
D
S
P
P
R
S
D
P
T
Chimpanzee
Pan troglodytes
XP_518487
508
51590
S224
T
C
L
N
S
P
D
S
P
P
R
S
D
P
T
Rhesus Macaque
Macaca mulatta
XP_001093365
508
51688
S224
T
C
L
N
S
P
D
S
P
P
R
S
D
P
T
Dog
Lupus familis
XP_852302
508
51510
S224
T
C
L
N
S
P
D
S
P
P
R
S
D
P
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9JM73
504
51229
S220
T
C
L
N
S
P
D
S
P
P
R
S
D
P
T
Rat
Rattus norvegicus
NP_001102772
504
51157
S220
T
C
L
N
S
P
D
S
P
P
R
S
D
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517936
150
15822
Chicken
Gallus gallus
Q90718
375
39146
S104
P
T
T
D
Q
R
M
S
A
T
G
F
E
E
T
Frog
Xenopus laevis
P23790
448
46097
P177
I
Q
T
C
L
N
S
P
D
S
P
P
R
S
D
Zebra Danio
Brachydanio rerio
NP_001103996
539
55032
D212
P
R
T
D
P
S
T
D
Q
R
M
S
A
T
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24535
449
47603
N177
I
K
M
E
Y
I
D
N
K
L
R
R
Y
T
T
Honey Bee
Apis mellifera
XP_001120126
351
36852
C79
K
R
T
T
S
D
V
C
Y
D
D
S
N
A
R
Nematode Worm
Caenorhab. elegans
NP_492296
327
35027
N56
K
I
K
M
E
Y
I
N
N
K
L
R
R
Y
T
Sea Urchin
Strong. purpuratus
XP_796790
410
43027
L139
Y
T
F
A
T
R
K
L
Q
P
M
I
T
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11746
286
32783
Q15
T
P
T
N
N
G
Q
Q
K
E
R
R
K
I
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.4
97.2
N.A.
96.4
96.6
N.A.
22.8
66.5
72.4
57.7
N.A.
35
33.4
28.7
33.8
Protein Similarity:
100
99.8
98.8
98
N.A.
97.4
97.6
N.A.
24
69.6
76.9
67.7
N.A.
48.8
40.3
41.1
45.6
P-Site Identity:
100
100
100
100
N.A.
100
93.3
N.A.
0
13.3
0
6.6
N.A.
20
13.3
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
0
26.6
0
13.3
N.A.
33.3
20
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
33
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
0
0
7
0
0
0
7
7
0
% A
% Cys:
0
40
0
7
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
14
0
7
47
7
7
7
7
0
40
0
7
% D
% Glu:
0
0
0
7
7
0
0
0
0
7
0
0
7
7
14
% E
% Phe:
0
0
7
0
0
0
0
0
0
0
0
7
0
0
0
% F
% Gly:
0
0
0
0
0
7
0
0
0
0
7
0
0
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
14
7
0
0
0
7
7
0
0
0
0
7
0
7
0
% I
% Lys:
14
7
7
0
0
0
7
0
14
7
0
0
7
0
0
% K
% Leu:
0
0
40
0
7
0
0
7
0
7
7
0
0
0
0
% L
% Met:
0
0
7
7
0
0
7
0
0
0
14
0
0
0
0
% M
% Asn:
0
0
0
47
7
7
0
14
7
0
0
0
7
0
0
% N
% Pro:
14
7
0
0
7
40
0
7
40
47
7
7
0
40
0
% P
% Gln:
0
7
0
0
7
0
7
7
14
0
0
0
0
0
0
% Q
% Arg:
0
14
0
0
0
14
0
0
0
7
54
20
14
0
7
% R
% Ser:
0
0
0
0
47
7
7
47
0
7
0
54
0
14
7
% S
% Thr:
47
14
34
7
7
0
7
0
0
7
0
0
7
14
54
% T
% Val:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
7
7
0
0
7
0
0
0
7
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _